Beilstein J. Org. Chem.2012,8, 170–176, doi:10.3762/bjoc.8.18
), (−)-4α,10β-aromadendranediol (8), (+)-4β,10β-aromadendranediol (9) were obtained from the South China Sea gorgonian coral Melitodessquamata Nutting. Compounds 1, 2, 6, and 7 were new, and their structures were established by spectroscopic analyses. Compounds 6 and 7 contained a taurine group that was
rarely found in marine natural compounds, and 7 showed moderate antibacterial activity. The possible biosynthesis routes of 1–5 were conjectured.
Keywords: carbamate; gorgonian; Melitodessquamata; sesquiterpenoid; Introduction
Gorgonians are recognized to mainly produce acetogenins, sesquiterpenoids
, diterpenoids, prostanoids, and steroids [1][2]. However, nitrogen-containing compounds were relatively few obtained from gorgonians. Gorgonian Melitodessquamata Nutting belonging to Melithaea family is a kind of pharmaceutical coral that has the efficacy of relieving cough, bleeding, and diarrhea, soothing